基本情况:彭小宁，男，博士，教授，吉首大学医学院院长，生物化学与分子生物学硕士生导师。湖南师范大学统计学博士生导师。湖南省十二五重点学科带头人，湖南省病理生理学会副理事长，湖南省预防医学常务理事。国际SCI刊物Journal of Cancer编委。从事生物信息,医学统计学和肿瘤基础研究工作已有近二十年时间，在芯片数据分析，遗传算法开发与运用，循证医学，生殖神经的肿瘤基因组数据挖掘和精准医学等领域开展研究。主持完成十多项国家自然科学基金面上、教育部留学归国人员启动基金和湖南省自然基金等科研项目。在Nature, Oncogene, Clinical Infectious Diseases,Translational Reaserch, PLoS One等杂志发表论文40余篇，研究成果被Nature Reviews Urology评为研究亮点。研究成果《幽门螺杆菌感染在肝癌发生中作用的研究》于2011年获得湖南省科技进步奖二等奖。
联系方式 ：Email:2407997518@qq.com（pxiaoning@hunnu.edu.cn）
代表性论文（*：通讯作者）:
1. Yue Li, Weiguo Li, Xiaomin Zeng, Xuemei Tang, Shan Zhang, Feiya Zhong, Xiangni Peng, Yang Zhong, Thomas J. Rosol , Xiyun Deng, Zhonghua Liu, Sihua Peng,Xiaoning Peng*.The role of microRNA-148a and downstream DLGAP1 on the molecular regulation and tumor progression on human glioblastoma. Oncogene 2019; https://doi.org/10.1038/s41388-019-0922-3
2. Li J, Lu YP, Tsuprykov O, Hasan AA, Reichetzeder C, Tian M, Zhang XL, Zhang Q, Sun GY, Guo J, Gaballa MMS,Peng XN, Lin G, Hocher B.Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet.Diabetologia. 2018 Aug;61(8):1862-1876.
3. Tan ZW, Xie S, Hu SY, Liao T, Liu P, Peng KH, Yang XZ, He ZL, Tang HY, Cui Y,Peng XN,Zhang J, Zhou C.Caudatin targets TNFAIP1/NF-κB and cytochrome c/caspase signaling to suppress tumor progression in human uterine cancer. Int J Oncol. 2016 Oct;49(4):1638-1650.
4.Yue Li, Xiyun Deng, Xiaomin Zeng,Xiaoning Peng*.The Role of Mir-148a in Cancer.Journal of Cancer. 2016, 7(10):1233-1241. doi: 10.7150/jca.14616.
5.Yang R, Xiong J, Deng D, Wang Y, Liu H, Jiang G, Peng Y, Peng X*, Zeng X. An integrated model of clinical information and gene expression for prediction of survival in ovarian cancer patients.Transl Res. 2016,Jun:172:84-95.e11. doi: 10.1016/j.trsl.2016.03.001.
6.Hao Li, Guangchun He, Hui Yao1, Liujiang Song, Liang Zeng,Xiaoning Peng, Thomas J. Rosol, Xiyun Deng. TGF-β Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma.Journal of Cancer. 2015, 6(6): 511-518. DOI: 10.7150/jca.10830.
7.Yong Zhang, Yanlin Su, Lesai Li, Zhi Yang1, Si Chen, Jie Xiong, Xiaohua Fu andXiaoning Peng*. Mouse dead end 1-β interacts with c-Jun and stimulates activator protein 1 transactivation.Molecular Medicine Reports. 2015,11: 1701-1707. DOI: 10.3892/mmr.2014.2950 .
8.Xiyun Deng , Guangchun He, Junwen Liu , Feijun Luo ,Xiaoning Peng , Shigang Tang , Zhiyong Gao , Qinlu Lin , Jill M. Keller , Tao Yang , Evan T. Keller. Recent advances in bone-targeted therapies of metastatic prostate cancer.Cancer Treatment Reviews.2014, 40:730–738. DOI: 10.1016/j.ctrv.2014.04.003.
9.Jie Xiong, Zhitong Bing, Yanlin Su, Defeng Deng,Xiaoning Peng*. An Integrated mRNA and microRNA Express ion Sig nature for Gliobl astoma Multifor me Prognosis.PLOS ONE. 2014, 9(5): e98419. DOI: 10.1371/journal.pone.0098419.
10.Yanlin Su, Jie Xiong, Zhitong Bing, Xiaomin Zeng,YongZhang, Xiaohua Fu andXiaoning Peng*. Identification of novel human glioblastoma-specific transcripts by serial analysis of gene expression data mining.Cancer Biomarkers. 2013,13(5):367-375. DOI: 10.3233/CBM-130367.
11.Xiaoning Peng*, Xiaomin Zeng, Sihua Peng, Defeng Deng，Jian Zhang. The Association Risk of Male Subfertility and Testicular Cancer: A Systematic Review.PLOS ONE. 2009,4(5): e5591. DOI: 10.1371/journal.pone.0005591).
12.Kirsten K. Youngren, Douglas Coveney,Xiaoning Peng, Chitralekha Bhattacharya, Laura S. Schmidt5, Michael L. Nickerson, Bruce T. Lamb, Jian Min Deng, Richard R. Behringer, Blanche Capel, Edward M. Rubin, Joseph H. Nadeau & Angabin Matin. The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours.Nature. 2005,435:360-364. DOI: 10.1038/nature03595.
13.Sihua Peng, Qianghua Xu, Xuefeng Bruce Ling,Xiaoning Peng, Wei Du, Liangbiao Chen. Molecular Classification of cancer types from microarray data using the combination of genetic algorithms and support vector machines.FEBS Letters. 2003, 555: 358-362. PMID: 14644442.
14.Xue-Gong Fan,Xiao-Ning Peng, Yan Huang, Javed Yakoob, Zhi-Ming Wang, and Yong-Ping Chen. Helicobacter species ribosomal DNA recovered from the liver tissue of Chinese patients with primary hepatocellular carcinoma.Clinical Infectious Diseases. 2002, 35:1555-7. DOI: 10.1086/344770.
15.Yakoob J, Fan XG,Peng XN, Hu GL, Zhang Z. Helicobater pylori cagA and vacA cytotoxin genes in Changsha, China. Br J Biomed Sci. 2002, 59(3):150-3. PMID: 12371056.)
