欧阳繁,男,教授,博士,硕士生导师,中国中部复杂冠脉介入青年委员会组长;中国医疗保健国际交流促进会心脏重症分会湖南省专业委员会常务委员;中国老年保健医学研究会老年心血管病分会委员;湖南省医学会心血管病学青年委员;湖南省医学会心血管病学专业委员会心脏重症学组委员;湖南省中医药和中西医结合学会重症医学专业委员会心血管重症学组委员;心血管疾病诊疗技术湖南省工程研究中心专家委员会委员;湖南省医学会心血管病专业委员会双心学组委员;株洲市心血管介入质控组组长;株洲市中心医院心内科主任,心内科导管室主任。2002年6月本科毕业于中南大学湘雅医学院临床医学专业,2013年6月硕士毕业于中南大学湘雅二医院心血管内科专业,2017年6月博士毕业于中南大学二医院内科学专业。研究兴趣:1. M2巨噬细胞外泌体lncRNA TINCR接到TGF-B/Smad通路促进心肌纤维化和心衰的机制研究;2.BI-1抗心肌缺血再灌注损伤的线粒体机制研究。主持国家自然科学基金项目1项,主持并完成省自然科学基金项目、市级科学研究重点项目等4项,发表SCI论文十余篇。
联系方式:1641261977@qq.com
代表性成果
1. Fan Ouyang , Xiangyang Liu , Guoan Liu , Haihua Qiu, Yi He 1, Hongyu Hu , Ping Jiang . Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation. Aging (Albany NY). 2020 Jan 8;12(1):996-1010. doi: 10.18632/aging.102463. Epub 2020 Jan 8.
2. Lei Wang , Ping Jiang , Yi He , Hongyu Hu , Yuan Guo , Xiangyang Liu , Haihua Qiu , Qilin Ma , Fan Ouyang *. A novel mechanism of Smads/miR-675/TGFβR1 axis modulating the proliferation and remodeling of mouse cardiac fibroblasts. J Cell Physiol. 2019 Nov;234(11):20275-20285. doi: 10.1002/jcp.28628. Epub 2019 Apr 5.
3. Fan Ouyang, Yi He , Shuhong Guo , Chengming Wang , Weiqing Liu , Yuan Guo. Coronary sinus reducer for the treatment of refractory angina. Int J Cardiol. 2019 Feb 15;277:27. doi: 10.1016/j.ijcard.2018.09.072.
4. Ping Jiang , Jian Wu , ShuHong Guo , Yi He , Fan OuYang. Atrial fibrillation and sleep apnea: A chicken and egg situation. Int J Cardiol. 2018 Nov 15;271:120. doi: 10.1016/j.ijcard.2018.05.053.
5. Xiaolin Zhou , Huibing Peng , Yafei Yin , He Huang , Jianping Zeng , Fan Ouyang *. Diffused alveolar hemorrhage: A rare and severe complication of tirofiban-induced thrombocytopenia. Int J Cardiol. 2016 Mar 1;206:93-4. doi: 10.1016/j.ijcard.2016.01.020.
6. Fan Ouyang , He Huang , Mingyu Zhang , Mingxian Chen , Haobo Huang , Fang Huang , Shenghua Zhou. HMGB1 induces apoptosis and EMT in association with increased autophagy following H/R injury in cardiomyocytes. Int J Mol Med. 2016 Mar;37(3):679-89. doi: 10.3892/ijmm.2016.2474. Epub 2016 Jan 29.
7. Fan Ouyang , Mingxian Chen , Ting Yi , Mingxing Wu , Huibing Peng , Haobo Huang , He Huang , Shenghua Zhou. Successful percutaneous coronary intervention for multivessel stenosis complicated by a huge coronary artery fistula with the combined physiology and intracoronary anatomy techniques. Int J Cardiol. 2015 Aug 1;192:70-1. doi: 10.1016/j.ijcard.2015.05.026. Epub 2015 May 8.
8. Fan Ouyang, Mingxing Wu, Huibing Peng, Mingyu Zhang, Haobo Huang, Mingxian Chen, He Huang, Shenghua Zhou. Fractional flow reserve, an effective preoperative guideline to a patient with a huge coronary artery fistula and tandem stenosis. Int J Cardiol. 2015 Nov 15;199:333-4. doi: 10.1016/j.ijcard.2015.06.135. Epub 2015 Jul 2.
9. Huibing Peng, Mingxian Chen, Guibing Li, Mingyu Zhang, Mingxing Wu , Haobo Huang, He Huang , Fan Ouyang *. Combination refusion therapy for a hemodynamically unstable patient with acute myocardial infarction complicated by acute ischemic stroke within a time window. Int J Cardiol. 2015 Dec 15;201:152-3. doi: 10.1016/j.ijcard.2015.08.017. Epub 2015 Aug 3.
10. Xiaoyong Hu , He Huang , Yafei Yin, Mingxing Wu , Jianping Zeng , Fan Ouyang *. Who is the culprit for the patient with acute myocardial infarction, plaque rupture or essential thrombocytosis? Int J Cardiol. 2016 Feb 1;204:175-6. doi: 10.1016/j.ijcard.2015.11.098.
11. Haobo Huang, Jianping Zeng, Yougen Kang, He Huang, Zan Hu, Weihua Zeng, Fan Ouyang *. Acute ischemia stroke: A rare and severe complication of ovarian hyperstimulation syndrome hyperstimulation syndrome plaque rupture or essential thrombocytosis? doi.org/10.1016/j.ijcard.2015.10.059.