吴波文，男，湘雅医学院兼职副教授，副主任医师，医学博士，硕士生导师，株洲市中心医院创伤中心副主任，骨科中心秘书。2006年6月本科毕业于南华大学医学院，2009年6月硕士毕业于暨南大学临床学院外科学专业。研究兴趣：1.骨肉瘤化疗的多药耐药机制；2.前列腺癌骨转移相关机制。主持湖南省自然科学基金项目1项，参与省市课题多项，发表论文10余篇（SCI论文6篇，CSCD论文5篇），实用新型专利2项，主编专著2部。

联系方式：wubowen03663@163.com

代表性成果

1. Cui Q, Zhu W, Zhao H, Zhu J, Wu B. Clinical significance of femoral cortical thickness parameters and trabecular density in the treatment of hip fracture in the elderly. Minerva Med. 2021 Oct 21.

2.吴波文,蔡伟良,刘欢欢,刘银,李洁,朱宝玉,曾伟.假体周围感染兔模型中D-二聚体的动态表达与感染时间和种植细菌量的相关性研究[J].中国中医骨伤科杂志,2021,29(11):7-12.

3. Wu B, Zeng W, Ouyang W, Xu Q, Chen J, Wang B, Zhang X. Quercetin induced NUPR1-dependent autophagic cell death by disturbing reactive oxygen species homeostasis in osteosarcoma cells. J Clin Biochem Nutr. 2020 Sep;67(2):137-145.

4. Tang Y, Wu B, Huang S, Peng X, Li X, Huang X, Zhou W, Xie P, He P. Downregulation of miR5053p predicts poor bone metastasisfree survival in prostate cancer. Oncol Rep. 2019 Jan;41(1):57-66. doi: 10.3892/or.2018.6826.

5. Kang Y, He P, Wang H, Ye Y, Li X, Xie P, Wu B. Brazilin induces FOXO3A-dependent autophagic cell death by disturbing calcium homeostasis in osteosarcoma cells. Cancer Chemother Pharmacol. 2018 Sep;82(3):479-491.

6. Cai W, Wu B, Li Z, He P, Wang B, Cai A, Zhang X. LncRNA NBR2 inhibits epithelial-mesenchymal transition by regulating Notch1 signaling in osteosarcoma cells. J Cell Biochem. 2018 Sep 6.

7. Wu B, Tan M, Cai W, Wang B, He P, Zhang X. Arsenic trioxide induces autophagic cell death in osteosarcoma cells via the ROS-TFEB signaling pathway. Biochem Biophys Res Commun. 2018 Jan 29;496(1):167-175.