郭媛,女,1989年3月,中南大学湘雅医学院附属株洲医院,心血管内科主治医师、副研究员,医学博士(后);博士生导师(中南大学)、硕士生导师(中南大学、南华大学、湖南工业大学、吉首大学);入选湖南省优秀博士后创新人才计划、2023年湖南省卫生健康高层次人才青年骨干人才。主要从事心脏康复与心血管疾病的临床、基础及转化研究;人工智能算法在心血管疾病中的应用研究等。先后主持国家自然科学基金、中国博士后科学基金面上项目及湖南省自然科学基金项目等省部级以上科研项目7项。以第一/通讯作者发表SCI论文24篇,累计影响因子142,单篇最高IF=12.4,其中1篇入选全球ESI 1%。授权国家专利2项,国际发明专利1项。研究成果获得湖南省自然科学奖三等奖、第十六届湖南省医学科技奖一等奖等。
联系方式:guoyuan0815@163.com
代表性论文(近5年,按时间倒序):
1.Chen F, He Z, Wang C, Si J, Chen Z*,Guo Y*. Advances in the study of S100A9 in cardiovascular diseases.Cell Prolif. 2024;e13636.(IF =8.5)
2. Guo Y, He Z, Chen Z, Chen F, Wang C, Zhou W, Liu J, Liu H, Shi R*. Inhibition of Th17 cells by donepezil ameliorates experimental lung fibrosis and pulmonary hypertension.Theranostics. 2023; 13(6):1826-1842.(IF = 12.4)
3. He Z, Liu C, Li Z, Chu Z, Chen X, Chen X, Guo Y*. Advances in the use of nanomaterials for nucleic acid detection in point-of-care testing devices: A review.Front Bioeng Biotech. 2022; 10:1020444.(IF = 6.06)
4. Chen Z, Zhao K, Xiao C, He Z, Liu S, Wu X, Shi S,Guo Y*. Phosphodiesterase inhibitor for heart failure with preserved ejection fraction: A systematic review and meta-analysis.Saudi Pharm J. 2022;30(8):1079-1087.(IF = 4.56)
5. Xiao C,Guo Y*, Zhao K, Liu S, He N, He Y, Guo S, and Chen Z*. Prognostic value of machine learning in patients with acute myocardial infarction.J. Cardiovasc Dev Dis, 2022, 9(2): 56.(IF= 4.42,ESI 1%)
6. Chen Z, Zhao K, He Z, Luo X, Qin Z, Tan Y, Zheng X, Wu Z, Deng Y, Chen H,Guo Y*, Li S*. Development and evaluation of a thermostatic nucleic acid testing device based on magnesium pyrophosphate precipitation for detecting Enterocytozoon hepatopenaei.Chinese Chem Lett. 2022,33:4053-4056.(IF=9.1)
7. Guo Y, Xiao C, Zhao K, He Z, Liu S, Wu X, Shi S, Chen Z, Shi R*. Physical Exercise Modalities for the Management of Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis. J Cardiovasc Pharmacol. 2022;79(5):698-710.(IF = 3.27)
8. Xu Y, Wang T, Chen Z*, Jin L, Wu Z, Yan J, Zhao X, Cai L, Deng Y,Guo Y*, Li S*, He N. The point-of-care-testing of nucleic acids by chip, cartridge and paper sensors.Chinese Chem Lett. 2021;32:3675-3686.(IF= 8.46)
9. Qiu H, Zhang Y, Li Z, Jiang P, Guo S, He Y,Guo Y*. Donepezil Ameliorates Pulmonary Arterial Hypertension by Inhibiting M2-Macrophage Activation.Front. Cardiovasc. Med. 2021; 8:639541.(IF= 5.85)
10. Chen Z, Xiao C, Qiu H, Tan X, He Y, Guo Y*, He N*. Recent advance of artificial intelligence in cardiovascular disease.J Biomed Nanotechnol. 2020; 16(7):1065.(IF= 4.09)
11. Guo Y*, Liu X, Zhang Y, Qiu H, Ouyang F, He Y. 3-Bromopyruvate ameliorates pulmonary arterial hypertension by improving mitochondrial metabolism.Life Sci. 2020; 256: 118009.(IF= 5.04)
12.Guo Y*, Chen J, Qiu H. Novel Mechanisms of Exercise-Induced Cardioprotective Factors in Myocardial Infarction.Front Physiol. 2020; 11:199.(IF= 4.56)
13. Qiu H, He Y, Ouyang F, Jiang P, Guo S,Guo Y*. The Role of Regulatory T Cells in Pulmonary Arterial Hypertension.J Am Heart Assoc. 2019; 8: e014201.(IF= 4.61)
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